We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
The International Journal of Oral & Maxillofacial Implants
Login:
username:

password:

Plattform:

Forgotten password?

Registration

Int J Oral Maxillofac Implants 26 (2011), No. 2     15. Apr. 2011
Int J Oral Maxillofac Implants 26 (2011), No. 2  (15.04.2011)

Page 245-250, PubMed:21483876


The Effect of Hydroxyapatite-Coated Titanium Fiber Web on Human Osteoblast Functional Activity
Hirota, Makoto / Hayakawa, Tohru / Ametani, Akihiro / Kuboki, Yoshinori / Sato, Mitsunobu / Tohnai, Iwai
Purpose: The aim of this study was to evaluate human osteoblast activity on thin hydroxyapatite (HA)-coated three-dimensional scaffolds made of titanium fiber web.
Materials and Methods: A thin HA film was coated on a titanium fiber web by the molecular precursor method. Human osteoblasts were disseminated onto the uncoated and HA-coated titanium fiber web, and osteoblast activity was observed at days 3, 7, 14, and 21 of culture.
Results: Proliferation activities of osteoblasts were significantly higher in the uncoated titanium fiber web. Osteoblasts in the uncoated titanium fiber web showed a typical expression pattern, but those in the HA-coated titanium fiber web showed rapid osteocalcin expression and calcification at an early stage of culture. Moreover, osteocalcin expression per osteoblast was significantly higher in the HA-coated group.
Conclusion: These results suggest that HA coating with the molecular precursor method accelerated osteoblast functional activity.

Keywords: functional activity, hydroxyapatite coating, molecular precursor method, osteoblast, titanium fiber web