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The International Journal of Oral & Maxillofacial Implants
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Int J Oral Maxillofac Implants 32 (2017), No. 5     19. Sep. 2017
Int J Oral Maxillofac Implants 32 (2017), No. 5  (19.09.2017)

Page 1135-1144, doi:10.11607/jomi.5577, PubMed:28906508


A Prospective Case-Control Clinical Study of Titanium-Zirconium Alloy Implants with a Hydrophilic Surface in Patients with Type 2 Diabetes Mellitus
Cabrera-Domínguez, José J. / Castellanos-Cosano, Lizett / Torres-Lagares, Daniel / Machuca-Portillo, Guillermo
Purpose: To evaluate prospectively the behavior of narrow-diameter (3.3-mm) titanium-zirconium alloy implants with a hydrophilic surface (Straumann Roxolid SLActive) in patients with type 2 diabetes mellitus in single-unit restorations, compared with a healthy control group (assessed using the glycosylated hemoglobin HbA1c test).
Materials and Methods: The patients evaluated in this study required single-unit implant treatment; 15 patients had type 2 diabetes mellitus, and 14 patients were healthy (control group [CG]). Marginal bone level (MBL) change around the implants was evaluated using conventional, sequential periapical digital radiographs. Patient HbA1c was assessed in each check-up. Normality test (Kolmogorov- Smirnov), univariate and multivariate logistic regression, analysis of variance (ANOVA), and Mann-Whitney U test were used for statistical analysis.
Results: No differences in MBL change and implant survival and success rates were found between the diabetes mellitus group (DMG) versus the control group, either during the initial recording (DMG, 0.99 ± 0.56 vs CG, 0.68 ± 0.54; P > .05) or 6 months after restoration (DMG, 1.28 ± 0.38 vs CG, 1.11 ± 0.59; P > .05). No significant correlation between HbA1c levels and MBL change was detected in these patients (P > .05).
Conclusion: Patients with glycemic control exhibit similar outcomes to healthy individuals with regard to the investigated parameters. In light of these findings, the titaniumzirconium alloy small-diameter implants can be used in the anterior region of the mouth in type 2 diabetic patients.

Keywords: glycosylated hemoglobin, small-diameter implants, titanium-zirconium implants, type 2 diabetes