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The International Journal of Oral & Maxillofacial Implants



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Int J Oral Maxillofac Implants 33 (2018), No. 1     9. Feb. 2018
Int J Oral Maxillofac Implants 33 (2018), No. 1  (09.02.2018)

Page 181-187, doi:10.11607/jomi.5928, PubMed:29340352

Bone Healing at Functionally Loaded and Unloaded Screw-Shaped Implants Supporting Single Crowns: A Histomorphometric Study in Humans
Yonezawa, Daichi / Piattelli, Adriano / Favero, Riccardo / Ferri, Mauro / Iezzi, Giovanna / Botticelli, Daniele
Purpose: To evaluate histologically and histomorphometrically the effect of a delayed load on healing at implants with a moderately rough surface.
Materials and Methods: Two solid titanium screw-shaped devices, 5 mm long and 3.5 mm in diameter, were inserted in the distal segments of the alveolar ridge of 16 volunteer patients in a nonsubmerged fashion. After 2 months, one implant was loaded, while the other was left unloaded. After 2 months, the two implants were collected from 10 patients using a sonic instrument, and ground sections were prepared from the biopsy specimens. Histomorphometric analyses were performed.
Results: After 4 months of healing, biopsy specimens from 10 patients were available for analyses (n = 10). The total bone-to-implant contact percentage was 86.8% ± 6.5% and 84.6% ± 3.7% for loaded and unloaded implants, respectively. New bone was represented by 85.5% ± 6.7% and 83.4% ± 3.9% at the loaded and unloaded sites, respectively. A very small amount of old parent bone was found. The density of the mineralized bone was 76.8% ± 8.3% for the loaded sites and 74.1% ± 10.5% for the unloaded sites. The percentages of new and old bone densities were 69.0% ± 8.3% and 7.8% ± 3.9% at the loaded sites, and 65.9% ± 10.3% and 8.2% ± 4.5% at the unloaded sites, respectively. No statistically significant differences were disclosed.
Conclusion: Applying a delayed load to implants supporting single crowns did not yield statistically significant differences, and only a tendency of higher osseointegration and bone density was observed at loaded sites compared with the unloaded sites.

Keywords: delayed load, dental implants, histometry, human study, morphometry, prosthetic reconstruction