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The International Journal of Oral & Maxillofacial Implants
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Int J Oral Maxillofac Implants 28 (2013), No. 2     15. Mar. 2013
Int J Oral Maxillofac Implants 28 (2013), No. 2  (15.03.2013)

Page 543-549, doi:10.11607/jomi.2647, PubMed:23527358


Simultaneous Sinus Augmentation with Implant Placement: Histomorphometric Comparison of Two Different Grafting Materials. A Multicenter Double-Blind Prospective Randomized Controlled Clinical Trial
Silvestri, Maurizio / Martegani, Paolo / D'Avenia, Ferdinando / Farneti, Mauro / Capri, Diego / Paolantoni, Guerino / Landi, Luca
Purpose: Sinus elevation via the lateral approach for implant rehabilitation of atrophic posterior maxillae is considered a safe and predictable therapy. Several xenogeneic biomaterials of different biologic origin have been used as valid and predictable alternatives to autogenous bone. This multicenter randomized controlled double-blind prospective clinical trial aimed to compare histomorphometrically two xenogeneic grafting materials used for sinus elevation with simultaneous implant placement.
Materials and Methods: Seven private practices in Italy were involved. Patients presenting at least one site with a residual bone crest height between 2 and 4 mm were treated. Control sites were grafted with 100% deproteinated particulated bovine bone (DPBB), while test sites were grafted with prehydrated corticocancellous porcine bone (PCPB). Root-form implants were placed simultaneously. Insertion torque and clinical stability were assessed and recorded. At 6 months, a biopsy specimen was harvested from each site, and histomorphometric analyses were performed.
Results: Thirty-seven patients received 42 sinus elevations (24 test and 18 control). Eighty-two implants with adequate primary stability were placed. Fifty-five implants were placed in residual bone crests greater than 2 mm but less than 4 mm (average 2.7 mm) and achieved an average insertion torque of 22.8 ± 11.3 N/cm. Nineteen implants were placed in ridges greater than 3 mm but less than 5 mm, and eight were placed in ridges with more than 5 mm remaining. After 6 months, three implants had failed to integrate, leading to a survival rate of 96.34%. Forty-two specimens were analyzed histomorphometrically. No significant differences in total bone volume (PCPB 37.43%, DPBB 37.52%) or residual grafting material (PCPB 13.55%, DPBB 16.44%) were detected.
Conclusions: In this study, PCPB compared well with DPBB as a grafting material for lateral sinus elevation.