Int J Oral Maxillofac Implants 28 (2013), No. 6 20. Dec. 2013
Int J Oral Maxillofac Implants 28 (2013), No. 6 (20.12.2013)
Online Article, Page 357-367, doi:10.11607/jomi.te16, PubMed:24278939
Online Article: The Use of a Magnesium-Based Bone Cement to Secure Immediate Dental Implants
Sehlke, Brandon M. / Wilson, Thomas G. / Jones, Archie A. / Yamashita, Motofumi / Cochran, David L.
Purpose: The use of a magnesium-based bone cement, OsteoCrete, has shown promise as a means to secure bone and tendon-to-bone connections in orthopedic medicine. The presence of a bone cement to fill the residual socket and stabilize a dental implant during healing could make immediate implant placement in molar sites more predictable. The aim of this study was to determine whether this magnesium-based bone cement can be used predictably for this purpose.
Materials and Methods: The mandibular third premolars and first molars were extracted bilaterally from four mongrel dogs (60 to 80 lb each). Implants were placed in each extraction socket and supported by only 2 to 3 mm of apical furcation bone. OsteoCrete bone cement was placed randomly for implant stabilization in half of the sites. Clinical healing was evaluated until the 4-month time point. All animals were then sacrificed, and mandibular en bloc resection was performed for histologic evaluation of the biologic response and bone-to-implant contact.
Results: Clinically, healing showed a poor response when the test site implant was left exposed in a one-stage manner. No statistically significant difference was noted in bone-to-implant contact (52% in test sites versus 44% in control sites). Histologic specimens showed no adverse biologic response to the material but only minimal replacement at 4 months.
Conclusions: OsteoCrete bone cement was successful in stabilizing the immediate dental implant in a large extraction socket when placed in a closed environment in the dog model but did not show a benefit as compared to controls. The limited data warrant further studies to determine the further potential of this material.